Secreting gastro-enteropancreatic neuroendocrine tumours and biomarkers
نویسندگان
چکیده
Secreting Gastro-enteropancreatic Neuroendocrine Tumours and Biomarkers 1 2 Wieke H.M. Verbeek 1* , Catharina M. Korse 2* , Margot E.T. Tesselaar 3* 3 Departments of 1 Gastroenterology, 2 Clinical Chemistry and 3 Medical Oncology 4 The Netherlands Cancer Institute – Antoni van Leeuwenhoek, Amsterdam 5 The Netherlands 6 * Equal contribution 7 8 Corresponding author: 9 Dr. M.E.T. Tesselaar, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. 10 Email: [email protected] 11 12 13 14
منابع مشابه
Analysis of sporadic neuroendocrine tumours of the enteropancreatic system by comparative genomic hybridisation.
BACKGROUND Chromosomal instability is observed in a wide spectrum of human cancer syndromes. However, to date, little is known of the characteristic genetic changes in sporadic neuroendocrine tumours of the gastroenteropancreatic system. AIMS AND METHOD We have studied copy number aberrations (CNAs) in 26 sporadic neuroendocrine tumours of the enteropancreatic system (12 foregut and 14 midgut...
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متن کاملCirculating biomarkers in neuroendocrine tumors of the enteropancreatic tract: application to diagnosis, monitoring disease, and as prognostic indicators.
Neuroendocrine tumors (NETs) are difficult to diagnose. Their symptoms may be vague or intermittent, and are frequently associated with much more common diseases; many of the tumors may be asymptomatic. Therefore, diagnosis can be delayed for some years. Because most NETs are secretory, the measurement of circulating biomarkers is helpful not only for diagnosis but also for assessing tumor resp...
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